ID   FD-LSC-1
AC   CVCL_S891
DR   cancercelllines; CVCL_S891
DR   Wikidata; Q54833431
RX   PubMed=24001612;
CC   Population: Chinese.
CC   Characteristics: Highly tumorigenic in NOD/SCID mice.
CC   Doubling time: 24 hours (PubMed=24001612).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Val173Leu (c.517G>T); ClinVar=VCV000376668; Zygosity=Unspecified (PubMed=24001612).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu287Ter (c.859G>T); Zygosity=Unspecified (PubMed=24001612).
CC   Derived from site: In situ; Larynx; UBERON=UBERON_0001737.
DI   NCIt; C4044; Laryngeal squamous cell carcinoma
DI   ORDO; Orphanet_494550; Squamous cell carcinoma of the larynx
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   68Y
CA   Cancer cell line
DT   Created: 03-02-14; Last updated: 19-12-24; Version: 13
//
RX   PubMed=24001612; DOI=10.1016/j.canlet.2013.08.041;
RA   Wu C.-P., Zhou L., Gong H.-L., Du H.-D., Tian J., Sun S., Li J.-Y.;
RT   "Establishment and characterization of a novel HPV-negative laryngeal
RT   squamous cell carcinoma cell line, FD-LSC-1, with missense and
RT   nonsense mutations of TP53 in the DNA-binding domain.";
RL   Cancer Lett. 342:92-103(2014).
//