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Cellosaurus PC-6/TAX1-1 (CVCL_S849)

[Text version]
Cell line name PC-6/TAX1-1
Synonyms PC-6/Tax1-1
Accession CVCL_S849
Resource Identification Initiative To cite this cell line use: PC-6/TAX1-1 (RRID:CVCL_S849)
Comments Population: Japanese.
Selected for resistance to: ChEBI; CHEBI:45863; Paclitaxel (Taxol).
Disease Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C002 (PC-6)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=10912951; DOI=10.1097/00001813-200006000-00005
Ishii M., Iwahana M., Mitsui I., Minami M., Imagawa S., Tohgo A., Ejima A.
Growth inhibitory effect of a new camptothecin analog, DX-8951f, on various drug-resistant sublines including BCRP-mediated camptothecin derivative-resistant variants derived from the human lung cancer cell line PC-6.
Anticancer Drugs 11:353-362(2000)

PubMed=17237272; DOI=10.1158/1535-7163.MCT-06-0529
Oguri T., Bessho Y., Achiwa H., Ozasa H., Maeno K., Maeda H., Sato S., Ueda R.
MRP8/ABCC11 directly confers resistance to 5-fluorouracil.
Mol. Cancer Ther. 6:122-127(2007)

PubMed=18445659; DOI=10.1158/1535-7163.MCT-07-2088
Oguri T., Ozasa H., Uemura T., Bessho Y., Miyazaki M., Maeno K., Maeda H., Sato S., Ueda R.
MRP7/ABCC10 expression is a predictive biomarker for the resistance to paclitaxel in non-small cell lung cancer.
Mol. Cancer Ther. 7:1150-1155(2008)

Cross-references
Encyclopedic resources Wikidata; Q54938463
Entry history
Entry creation03-Feb-2014
Last entry update21-Mar-2023
Version number8