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Cellosaurus H69VZ (CVCL_S830)

[Text version]
Cell line name H69VZ
Synonyms MOG-H69VZ
Accession CVCL_S830
Resource Identification Initiative To cite this cell line use: H69VZ (RRID:CVCL_S830)
Comments Population: Caucasian.
Doubling time: 34.5 hours (PubMed=1662924).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; 8975; PIK3CA; Simple; p.Gly106_Arg108del (c.317_325delGGCAACCGT); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 9884; RB1; Simple; p.Glu748Ter (c.2242G>T); ClinVar=VCV000013078; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Glu171Ter (c.511G>T); ClinVar=VCV000634771; Zygosity=Homozygous (from parent cell line).
Disease Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1579 (NCI-H69)
Sex of cell Male
Age at sampling 55Y
Category Cancer cell line
Publications

PubMed=1662924
Khan M.Z., Freshney R.I., Murray A.M.B., Merry S., Plumb J.A., McNicol A.M.
Identification and characterisation in vitro of cells with a non-SCLC cell-like phenotype derived from a continuous SCLC cell line.
Anticancer Res. 11:1687-1695(1991)

PubMed=8712684
Khan M.Z., McNicol A.M., Freshney R.I.
Tumorigenicity, invasion and metastasis of the small cell lung cancer cell line NCI-H69 and two derivative lines MOG-H69V and MOG-H69VZ.
Anticancer Res. 16:1659-1669(1996)

Cross-references
Cell line databases/resources cancercelllines; CVCL_S830
Encyclopedic resources Wikidata; Q54872209
Entry history
Entry creation03-Feb-2014
Last entry update05-Oct-2023
Version number18