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Cellosaurus 402-91/ET (CVCL_S814)

[Text version]
Cell line name 402-91/ET
Accession CVCL_S814
Resource Identification Initiative To cite this cell line use: 402-91/ET (RRID:CVCL_S814)
Comments Selected for resistance to: ChEBI; CHEBI_84050; Trabectedin (Ecteinascidin-743; ET-743).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Sequence variations
  • Gene fusion; HGNC; HGNC:2726; DDIT3 + HGNC; HGNC:4010; FUS; Name(s)=FUS-DDIT3, TLS-CHOP (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Myxoid liposarcoma (NCIt: C27781)
Myxoid/round cell liposarcoma (ORDO: Orphanet_99967)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_S813 (402-91)
Sex of cell Male
Category Transformed cell line
Publications

PubMed=21805478; DOI=10.1002/ijc.26340
Uboldi S., Bernasconi S., Romano M., Marchini S., Fuso Nerini I., Damia G., Ganzinelli M., Marangon E., Sala F., Clivio L., Chiorino G., Di Giandomenico S., Rocchi M., Capozzi O., Margison G.P., Watson A.J., Caccuri A.M., Pastore A., Fossati A., Mantovani R., Grosso F., Tercero J.C., Erba E., D'Incalci M.
Characterization of a new trabectedin-resistant myxoid liposarcoma cell line that shows collateral sensitivity to methylating agents.
Int. J. Cancer 131:59-69(2012)

Cross-references
Encyclopedic resources Wikidata; Q54602863
Entry history
Entry creation03-Feb-2014
Last entry update19-Dec-2024
Version number11