ID   RBL20
AC   CVCL_S620
DR   DSMZ; ACC-944
DR   Wikidata; Q54949357
RX   PubMed=2090524;
RX   PubMed=2365495;
CC   Doubling time: 14 days (PubMed=2365495); 1-2 weeks (Note=After thawing), ~5-8 days (Note=At later passages) (DSMZ=ACC-944).
CC   Sequence variation: Gene deletion; HGNC; HGNC:9884; RB1; Zygosity=Heterozygous (DSMZ=ACC-944).
CC   Sequence variation: Mutation; HGNC; HGNC:9884; RB1; Simple; c.607+1G>T (IVS6+1G>T); ClinVar=VCV000013093; Zygosity=Heterozygous; Note=Splice donor mutation (DSMZ=ACC-944).
CC   Derived from site: In situ; Eye; UBERON=UBERON_0000970.
ST   Source(s): DSMZ=ACC-944
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D13S317: 9
ST   D16S539: 11
ST   D18S51: 12,14
ST   D19S433: 15,16
ST   D21S11: 28,33.2
ST   D2S1338: 17,20
ST   D3S1358: 14,17
ST   D5S818: 11,12
ST   D7S820: 9,10
ST   D8S1179: 12,14
ST   FGA: 21,22
ST   Penta D: 12
ST   Penta E: 7
ST   TH01: 6,8
ST   TPOX: 8,11
ST   vWA: 16,20
DI   NCIt; C8713; Bilateral retinoblastoma
DI   ORDO; Orphanet_790; Retinoblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   1Y4M
CA   Cancer cell line
DT   Created: 03-02-14; Last updated: 19-12-24; Version: 13
//
RX   PubMed=2090524; DOI=10.1111/j.1432-0436.1990.tb00479.x;
RA   Griegel S., Heise K., Kindler-Rohrborn A., Rajewsky M.F.;
RT   "In vitro differentiation of human retinoblastoma cells into neuronal
RT   phenotypes.";
RL   Differentiation 45:250-257(1990).
//
RX   PubMed=2365495; DOI=10.1002/ijc.2910460123;
RA   Griegel S., Hong C., Frotschl R., Hulser D.F., Greger V.,
RA   Horsthemke B., Rajewsky M.F.;
RT   "Newly established human retinoblastoma cell lines exhibit an
RT   'immortalized' but not an invasive phenotype in vitro.";
RL   Int. J. Cancer 46:125-132(1990).
//