Cellosaurus logo
expasy logo

Cellosaurus RBL18 (CVCL_S619)

[Text version]
Cell line name RBL18
Accession CVCL_S619
Resource Identification Initiative To cite this cell line use: RBL18 (RRID:CVCL_S619)
Comments Doubling time: 9 days (PubMed=2365495; DSMZ=ACC-913).
Derived from site: In situ; Eye; UBERON=UBERON_0000970.
Sequence variations
  • Mutation; HGNC; HGNC:9884; RB1; Simple; p.Met484Valfs*8 (c.1450_1451delAT); ClinVar=VCV000855427; Zygosity=Homozygous (DSMZ=ACC-913).
Disease Unilateral retinoblastoma (NCIt: C8714)
Retinoblastoma (ORDO: Orphanet_790)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 1Y3M
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-913

Markers:
AmelogeninX,Y
CSF1PO9,10
D2S133817,19
D3S135815,18
D5S81813
D7S82010
D8S117910,15
D13S31711
D16S53914
D18S5113,16
D19S43314,15
D21S1128,29
FGA19,24
Penta D13,16
Penta E11,13
TH019,10
TPOX8,11
vWA18,19

Run an STR similarity search on this cell line
Publications

PubMed=2090524; DOI=10.1111/j.1432-0436.1990.tb00479.x
Griegel S., Heise K., Kindler-Rohrborn A., Rajewsky M.F.
In vitro differentiation of human retinoblastoma cells into neuronal phenotypes.
Differentiation 45:250-257(1990)

PubMed=2365495; DOI=10.1002/ijc.2910460123
Griegel S., Hong C., Frotschl R., Hulser D.F., Greger V., Horsthemke B., Rajewsky M.F.
Newly established human retinoblastoma cell lines exhibit an 'immortalized' but not an invasive phenotype in vitro.
Int. J. Cancer 46:125-132(1990)

PubMed=7959682; DOI=10.1007/BF00211013
Greger V., Debus N., Lohmann D.R., Hopping W., Passarge E., Horsthemke B.
Frequency and parental origin of hypermethylated RB1 alleles in retinoblastoma.
Hum. Genet. 94:491-496(1994)

Cross-references
Cell line collections (Providers) DSMZ; ACC-913
Cell line databases/resources DSMZCellDive; ACC-913
Encyclopedic resources Wikidata; Q54949355
Entry history
Entry creation03-Feb-2014
Last entry update19-Dec-2024
Version number14