ID   WERI-Rb-27
AC   CVCL_S610
SY   WERI-Rb27; WERI-RB27; W-27; Wills Eye Research Institute-Retinoblastoma-27
DR   Wikidata; Q54993784
RX   PubMed=1679230;
RX   PubMed=2391623;
CC   Problematic cell line: Contaminated. Shown to be a Y-79 derivative (PubMed=1679230). Originally thought to originate from a 2 year old boy with a bilateral retinoblastoma.
CC   Population: Caucasian.
CC   Doubling time: 1.9 days (PubMed=2391623).
CC   Sequence variation: Mutation; HGNC; 9884; RB1; Unexplicit; Ex2-6del; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 9884; RB1; Unexplicit; IVS20+1G>A; Zygosity=Heterozygous (from parent cell line).
CC   Derived from sampling site: Eye; globe.
DI   NCIt; C7541; Retinoblastoma
DI   ORDO; Orphanet_790; Retinoblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1893 ! Y-79
SX   Female
AG   2Y6M
CA   Cancer cell line
DT   Created: 03-02-14; Last updated: 21-03-23; Version: 14
//
RX   PubMed=1679230; DOI=10.3109/13816819109023085;
RA   Madreperla S.A., Bookstein R., Jones O.W., Lee W.-H.;
RT   "Retinoblastoma cell lines Y79, RB355 and WERI-Rb27 are genetically
RT   related.";
RL   Ophthalmic Paediatr. Genet. 12:49-56(1991).
//
RX   PubMed=2391623; DOI=10.3928/0191-3913-19900701-11;
RA   Sery T.W., Lee E.Y.-H.P., Lee W.-H., Bookstein R., Wong V.,
RA   Shields J.A., Augsburger J.J., Donoso L.A.;
RT   "Characteristics of two new retinoblastoma cell lines: WERI-Rb24 and
RT   WERI-Rb27.";
RL   J. Pediatr. Ophthalmol. Strabismus 27:212-217(1990).
//