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Cellosaurus R06E (CVCL_S504)

[Text version]
Cell line name R06E
Synonyms R-06E; RO6E; AGE1.R06E; AGE1.RO
Accession CVCL_S504
Resource Identification Initiative To cite this cell line use: R06E (RRID:CVCL_S504)
Comments Group: Bat cell line.
Group: Patented cell line.
Problematic cell line: Partially contaminated. Some cultures of R06E are contaminated with the Vero cell line (PubMed=22754654), this is the case of the culture used in PubMed=20808767.
From: ProBioGen AG; Berlin; Germany.
Registration: International Depositary Authority, Deutsche Sammlung von Mikroorganismen und Zellkulturen (DSMZ); ACC-2902.
Virology: Not susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33389257).
Doubling time: ~50 hours (PubMed=19540275); ~40 hours (DSMZ=ACC-756).
Transformant: NCBI_TaxID; 28285; Adenovirus 5 [E1].
Species of origin Rousettus aegyptiacus (Egyptian rousette) (Egyptian fruit bat) (NCBI Taxonomy: 9407)
Originate from same individual CVCL_Z551 ! R05R
Sex of cell Sex unspecified
Age at sampling Fetus
Category Transformed cell line
Web pages http://www.plosntds.org/annotation/listThread.action?root=10229
https://www.probiogen.de/virus-production-cell-lines.html
Publications

PubMed=19540275; DOI=10.1016/j.virusres.2009.06.007
Jordan I., Horn D., Oehmke S., Leendertz F.H., Sandig V.
Cell lines from the Egyptian fruit bat are permissive for modified vaccinia Ankara.
Virus Res. 145:54-62(2009)

PubMed=20808767; DOI=10.1371/journal.pntd.0000802
Krahling V., Dolnik O., Kolesnikova L., Schmidt-Chanasit J., Jordan I., Sandig V., Gunther S., Becker S.
Establishment of fruit bat cells (Rousettus aegyptiacus) as a model system for the investigation of filoviral infection.
PLoS Negl. Trop. Dis. 4:e802.1-e802.9(2010)

PubMed=22754654; DOI=10.3390/v4050889
Jordan I., Munster V.J., Sandig V.
Authentication of the R06E fruit bat cell line.
Viruses 4:889-900(2012)

Patent=US8679839
Jordan I., Horn D., Sandig V.
Cell line from Rousettus as host cell for pathogen amplification.
Patent number US8679839, 25-Mar-2014

PubMed=33389257; DOI=10.1007/s10096-020-04106-0
Wurtz N., Penant G., Jardot P., Duclos N., La Scola B.
Culture of SARS-CoV-2 in a panel of laboratory cell lines, permissivity, and differences in growth profile.
Eur. J. Clin. Microbiol. Infect. Dis. 40:477-484(2021)

Cross-references
Cell line collections (Providers) BEI_Resources; NR-49168
DSMZ; ACC-756
Cell line databases/resources DSMZCellDive; ACC-756
Encyclopedic resources Wikidata; Q54948982
Entry history
Entry creation03-Feb-2014
Last entry update21-Mar-2023
Version number15