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Cellosaurus A2780-E(80) (CVCL_S476)

[Text version]
Cell line name A2780-E(80)
Synonyms A2780 E(80)
Accession CVCL_S476
Resource Identification Initiative To cite this cell line use: A2780-E(80) (RRID:CVCL_S476)
Comments Population: African American.
Selected for resistance to: ChEBI; CHEBI_27899; Cisplatin (CDDP).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Sequence variations
  • Mutation; HGNC; HGNC:795; ATM; Simple; p.Pro604Ser (c.1810C>T); ClinVar=VCV000127343; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Lys128_Arg130del (c.383_391del9); Zygosity=Unspecified (from parent cell line).
Disease Ovarian endometrioid adenocarcinoma (NCIt: C7979)
Endometrioid carcinoma of ovary (ORDO: Orphanet_454723)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_H619 (A2780-1A9)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=10772682; DOI=10.1093/jnci/92.8.642
Vandier D., Calvez V., Massaad-Massade L., Gouyette A., Mickley L.A., Fojo A., Rixe O.
Transactivation of the metallothionein promoter in cisplatin-resistant cancer cells: a specific gene therapy strategy.
J. Natl. Cancer Inst. 92:642-647(2000)

Cross-references
Cell line databases/resources cancercelllines; CVCL_S476
Encyclopedic resources Wikidata; Q54606577
Entry history
Entry creation03-Feb-2014
Last entry update19-Dec-2024
Version number15