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Cellosaurus NZM038 (CVCL_S450)

[Text version]
Cell line name NZM038
Synonyms NZM38
Accession CVCL_S450
Resource Identification Initiative To cite this cell line use: NZM038 (RRID:CVCL_S450)
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (PubMed=23658559; PubMed=32567790).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (PubMed=32567790).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Cancer cell line
STR profile Source(s): PubMed=32567790

Markers:
AmelogeninX
CSF1PO11,13
D2S133820
D3S135815,17
D5S81811,12
D7S8209,10
D8S117912,13
D13S3179,12
D16S53912,13
D18S5113,14
D19S43314
D21S1131,32.2
FGA22,24
TH017,8
TPOX8,10
vWA17,18

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Publications

PubMed=23658559; DOI=10.3389/fgene.2013.00066; PMCID=PMC3647113
Stones C.J., Kim J.E., Joseph W.R., Leung E.Y., Marshall E.S., Finlay G.J., Shelling A.N., Baguley B.C.
Comparison of responses of human melanoma cell lines to MEK and BRAF inhibitors.
Front. Genet. 4:66.1-66.6(2013)

PubMed=32567790; DOI=10.1111/pcmr.12908; PMCID=PMC7818249
Tran K.B., Gimenez G., Tsai P., Kolekar S., Rodger E.J., Chatterjee A., Jabed A., Shih J.-H., Joseph W.R., Marshall E.S., Wang Q., Print C.G., Eccles M.R., Baguley B.C., Shepherd P.R.
Genomic and signalling pathway characterization of the NZM panel of melanoma cell lines: a valuable model for studying the impact of genetic diversity in melanoma.
Pigment Cell Melanoma Res. 34:136-143(2021)

Cross-references
Cell line databases/resources cancercelllines; CVCL_S450
Encyclopedic resources Wikidata; Q54931570
Polymorphism and mutation databases Cosmic; 2007671
Entry history
Entry creation05-Nov-2013
Last entry update19-Dec-2024
Version number14