ID   BS153
AC   CVCL_S444
SY   BS-153
DR   Wikidata; Q54798328
RX   PubMed=11431328;
RX   PubMed=22570425;
RX   PubMed=23877316;
CC   Characteristics: Highly overexpresses EGFR (~50 fold). Overexpress the EGFRvIII splice isoform.
CC   Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (PubMed=11431328).
CC   Derived from site: In situ; Brain; UBERON=UBERON_0000955.
ST   Source(s): PubMed=22570425
ST   Amelogenin: X
ST   CSF1PO: 10,12
ST   D13S317: 12
ST   D16S539: 9
ST   D18S51: 12,17
ST   D21S11: 28,29
ST   D3S1358: 17
ST   D5S818: 11,13
ST   D7S820: 9,11
ST   D8S1179: 13
ST   FGA: 21,22
ST   Penta D: 9,14
ST   Penta E: 7
ST   TH01: 6,9
ST   TPOX: 11
ST   vWA: 15,18
DI   NCIt; C3058; Glioblastoma
DI   ORDO; Orphanet_360; Glioblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 05-11-13; Last updated: 29-06-23; Version: 9
//
RX   PubMed=11431328;
RA   Jones G., Machado J. Jr., Merlo A.;
RT   "Loss of focal adhesion kinase (FAK) inhibits epidermal growth factor
RT   receptor-dependent migration and induces aggregation of NH(2)-terminal
RT   FAK in the nuclei of apoptotic glioblastoma cells.";
RL   Cancer Res. 61:4978-4981(2001).
//
RX   PubMed=22570425; DOI=10.1093/neuonc/nos072; PMCID=PMC3367844;
RA   Bady P., Diserens A.-C., Castella V., Kalt S., Heinimann K.,
RA   Hamou M.-F., Delorenzi M., Hegi M.E.;
RT   "DNA fingerprinting of glioma cell lines and considerations on
RT   similarity measurements.";
RL   Neuro-oncol. 14:701-711(2012).
//
RX   PubMed=23877316; DOI=10.1093/neuonc/not093; PMCID=PMC3779041;
RA   Schulte A., Liffers K., Kathagen-Buhmann A., Riethdorf S., Zapf S.,
RA   Merlo A., Kolbe K., Westphal M., Lamszus K.;
RT   "Erlotinib resistance in EGFR-amplified glioblastoma cells is
RT   associated with upregulation of EGFRvIII and PI3Kp110delta.";
RL   Neuro-oncol. 15:1289-1301(2013).
//