ID   NZM033
AC   CVCL_S440
SY   NZM33
DR   BioSample; SAMN14558334
DR   cancercelllines; CVCL_S440
DR   Cosmic; 2007666
DR   Wikidata; Q54931565
RX   CelloPub=CLPUB00227;
RX   PubMed=23658559;
RX   PubMed=32567790;
CC   Doubling time: 62.4 hours (CelloPub=CLPUB00227).
CC   HLA typing: A*02:01,02:05; B*50:01,51:01; C*01:02,06:02 (PubMed=32567790).
CC   Sequence variation: Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Arg (c.182A>G); ClinVar=VCV000013900; Zygosity=Homozygous (PubMed=23658559; PubMed=32567790).
CC   Omics: Deep exome analysis.
CC   Omics: Transcriptome analysis by RNAseq.
ST   Source(s): PubMed=32567790
ST   Amelogenin: X,Y
ST   CSF1PO: 12
ST   D13S317: 12,15
ST   D16S539: 13
ST   D18S51: 12,13
ST   D19S433: 12,13
ST   D21S11: 27,30
ST   D2S1338: 17,26
ST   D3S1358: 17
ST   D5S818: 11
ST   D7S820: 11
ST   D8S1179: 11,13
ST   FGA: 19,24
ST   TH01: 9,9.3
ST   TPOX: 11
ST   vWA: 14,19
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
CA   Cancer cell line
DT   Created: 05-11-13; Last updated: 19-12-24; Version: 13
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RX   CelloPub=CLPUB00227;
RA   Daukste L.;
RT   "Mathematical modelling of cancer cell population dynamics.";
RL   Thesis PhD (2012); University of Canterbury; Christchurch; New Zealand.
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RX   PubMed=23658559; DOI=10.3389/fgene.2013.00066; PMCID=PMC3647113;
RA   Stones C.J., Kim J.E., Joseph W.R., Leung E.Y., Marshall E.S.,
RA   Finlay G.J., Shelling A.N., Baguley B.C.;
RT   "Comparison of responses of human melanoma cell lines to MEK and BRAF
RT   inhibitors.";
RL   Front. Genet. 4:66.1-66.6(2013).
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RX   PubMed=32567790; DOI=10.1111/pcmr.12908; PMCID=PMC7818249;
RA   Tran K.B., Gimenez G., Tsai P., Kolekar S., Rodger E.J.,
RA   Chatterjee A., Jabed A., Shih J.-H., Joseph W.R., Marshall E.S.,
RA   Wang Q., Print C.G., Eccles M.R., Baguley B.C., Shepherd P.R.;
RT   "Genomic and signalling pathway characterization of the NZM panel of
RT   melanoma cell lines: a valuable model for studying the impact of
RT   genetic diversity in melanoma.";
RL   Pigment Cell Melanoma Res. 34:136-143(2021).
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