ID   NZM028
AC   CVCL_S433
SY   NZM28
DR   BioSample; SAMN14558330
DR   cancercelllines; CVCL_S433
DR   Cosmic; 2007662
DR   Wikidata; Q54931559
RX   CelloPub=CLPUB00227;
RX   PubMed=23658559;
RX   PubMed=23755070;
RX   PubMed=32567790;
CC   Doubling time: 38.4 hours (CelloPub=CLPUB00227).
CC   HLA typing: A*01:01,03:01; B*35:01,44:02; C*04:01,05:01 (PubMed=32567790).
CC   Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Gly469Ala (c.1406G>C); ClinVar=VCV000013971; Zygosity=Heterozygous (PubMed=23658559; PubMed=32567790).
CC   Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Leu584Phe (c.1750C>T); ClinVar=VCV000802374; Zygosity=Heterozygous (PubMed=23658559; PubMed=32567790).
CC   Omics: Deep exome analysis.
CC   Omics: Transcriptome analysis by RNAseq.
ST   Source(s): PubMed=32567790
ST   Amelogenin: X,Y
ST   CSF1PO: 11,13
ST   D13S317: 12,14
ST   D16S539: 10,11
ST   D18S51: 13
ST   D19S433: 13,14
ST   D21S11: 29,30
ST   D2S1338: 17,18
ST   D3S1358: 15,16
ST   D5S818: 11,12
ST   D7S820: 10
ST   D8S1179: 13,14
ST   FGA: 21
ST   TH01: 6,7
ST   TPOX: 10,11
ST   vWA: 16,18
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
CA   Cancer cell line
DT   Created: 05-11-13; Last updated: 19-12-24; Version: 15
//
RX   CelloPub=CLPUB00227;
RA   Daukste L.;
RT   "Mathematical modelling of cancer cell population dynamics.";
RL   Thesis PhD (2012); University of Canterbury; Christchurch; New Zealand.
//
RX   PubMed=23658559; DOI=10.3389/fgene.2013.00066; PMCID=PMC3647113;
RA   Stones C.J., Kim J.E., Joseph W.R., Leung E.Y., Marshall E.S.,
RA   Finlay G.J., Shelling A.N., Baguley B.C.;
RT   "Comparison of responses of human melanoma cell lines to MEK and BRAF
RT   inhibitors.";
RL   Front. Genet. 4:66.1-66.6(2013).
//
RX   PubMed=23755070; DOI=10.3389/fgene.2013.00097; PMCID=PMC3668138;
RA   Kim J.E., Leung E.Y., Baguley B.C., Finlay G.J.;
RT   "Heterogeneity of expression of epithelial-mesenchymal transition
RT   markers in melanocytes and melanoma cell lines.";
RL   Front. Genet. 4:97.1-97.8(2013).
//
RX   PubMed=32567790; DOI=10.1111/pcmr.12908; PMCID=PMC7818249;
RA   Tran K.B., Gimenez G., Tsai P., Kolekar S., Rodger E.J.,
RA   Chatterjee A., Jabed A., Shih J.-H., Joseph W.R., Marshall E.S.,
RA   Wang Q., Print C.G., Eccles M.R., Baguley B.C., Shepherd P.R.;
RT   "Genomic and signalling pathway characterization of the NZM panel of
RT   melanoma cell lines: a valuable model for studying the impact of
RT   genetic diversity in melanoma.";
RL   Pigment Cell Melanoma Res. 34:136-143(2021).
//