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Cellosaurus NZM035 (CVCL_S427)

[Text version]
Cell line name NZM035
Synonyms NZM35
Accession CVCL_S427
Resource Identification Initiative To cite this cell line use: NZM035 (RRID:CVCL_S427)
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (PubMed=32567790).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (PubMed=32567790).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): PubMed=32567790

Markers:
AmelogeninX,Y
CSF1PO11,13
D2S133817,21
D3S135814,15
D5S81811,12
D7S8208,10
D8S117910,12
D13S31711,12
D16S5399,10
D18S5117
D19S43313,15.2
D21S1129,32.2
FGA22,26
TH019,9.3
TPOX8,9
vWA17

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Publications

PubMed=23658559; DOI=10.3389/fgene.2013.00066; PMCID=PMC3647113
Stones C.J., Kim J.E., Joseph W.R., Leung E.Y., Marshall E.S., Finlay G.J., Shelling A.N., Baguley B.C.
Comparison of responses of human melanoma cell lines to MEK and BRAF inhibitors.
Front. Genet. 4:66.1-66.6(2013)

PubMed=32567790; DOI=10.1111/pcmr.12908; PMCID=PMC7818249
Tran K.B., Gimenez G., Tsai P., Kolekar S., Rodger E.J., Chatterjee A., Jabed A., Shih J.-H., Joseph W.R., Marshall E.S., Wang Q., Print C.G., Eccles M.R., Baguley B.C., Shepherd P.R.
Genomic and signalling pathway characterization of the NZM panel of melanoma cell lines: a valuable model for studying the impact of genetic diversity in melanoma.
Pigment Cell Melanoma Res. 34:136-143(2021)

Cross-references
Cell line databases/resources cancercelllines; CVCL_S427
Encyclopedic resources Wikidata; Q54931567
Polymorphism and mutation databases Cosmic; 2007668
Entry history
Entry creation05-Nov-2013
Last entry update19-Dec-2024
Version number11