Cellosaurus cell line MSC 80 (CVCL

Cellosaurus MSC 80 (CVCL_S187)

Cross-references
Cell line name	MSC 80
Synonyms	MSC-80; MSC80; Mouse Schwann Cell line 80
Accession	CVCL_S187
Resource Identification Initiative	To cite this cell line use: MSC 80 (RRID:CVCL_S187)
Comments	Characteristics: Can be infected in vitro with mouse scrapie prion (PrPSc) and will continue to produce PrPSc after 18 passages and is able to transmit the prion disease to mice. Doubling time: 17 hours (PubMed=1629940). Omics: Cell surface proteome. Derived from site: In situ; Peripheral nervous system, sciatic nerve; UBERON=UBERON_0001322. Cell type: Schwann cell; CL=CL_0002573.
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090) Breed/subspecies: C57BL/6 x DBA/2.
Category	Spontaneously immortalized cell line
Publications	PubMed=1629940; DOI=10.1002/jnr.490320103 Boutry J.-M., Hauw J.-J., Gansmuller A., Di-Bert N., Pouchelet M., Baron-Van Evercooren A. Establishment and characterization of a mouse Schwann cell line which produces myelin in vivo. J. Neurosci. Res. 32:15-26(1992) PubMed=11836421; DOI=10.1128/JVI.76.5.2434-2439.2002; PMCID=PMC135945 Follet J., Lemaire-Vieille C., Blanquet-Grossard F., Podevin-Dimster V., Lehmann S., Chauvin J.-P., Decavel J.-P., Varea R., Grassi J., Fontes M., Cesbron J.-Y. PrP expression and replication by Schwann cells: implications in prion spreading. J. Virol. 76:2434-2439(2002) Patent=US7001767 Blanquet-Grossard F., Cesbron J.-Y., Lemaire-Vieille C., Follet J. Method for in vitro propagation of the agent responsible for transmissible spongiform encephalopathies. Patent number US7001767, 21-Feb-2006 PubMed=25894527; DOI=10.1371/journal.pone.0121314; PMCID=PMC4404347 Bausch-Fluck D., Hofmann A., Bock T., Frei A.P., Cerciello F., Jacobs A., Moest H., Omasits U., Gundry R.L., Yoon C., Schiess R., Schmidt A., Mirkowska P., Hartlova A.S., Van Eyk J.E., Bourquin J.-P., Aebersold R., Boheler K.R., Zandstra P.W., Wollscheid B. A mass spectrometric-derived cell surface protein atlas. PLoS ONE 10:E0121314-E0121314(2015)
Encyclopedic resources	Wikidata; Q54906813
Proteomic databases	PRIDE; PXD000589
Entry history
Entry creation	05-Nov-2013
Last entry update	29-Jun-2023
Version number	9