ID   CHO irs-20
AC   CVCL_S167
SY   CHO irs 20; irs-20; Irs-20; IRS-20; irs20
DR   Wikidata; Q54812585
RX   PubMed=7504309;
RX   PubMed=7910196;
RX   PubMed=8248482;
RX   PubMed=9008208;
RX   PubMed=9518490;
CC   Sequence variation: Mutation; UniProtKB; A0A061I8A6; Prkdc; Simple; p.Glu4090Lys (c.11268G>A); Zygosity=Heterozygous (PubMed=9518490).
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_S165 ! CHO-10B2
SX   Female
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 05-11-13; Last updated: 30-01-24; Version: 11
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RX   PubMed=7504309; DOI=10.2307/3578617;
RA   Stackhouse M.A., Bedford J.S.;
RT   "An ionizing radiation-sensitive mutant of CHO cells: irs-20. I.
RT   Isolation and initial characterization.";
RL   Radiat. Res. 136:241-249(1993).
//
RX   PubMed=7910196; DOI=10.1080/09553009414550661;
RA   Stackhouse M.A., Bedford J.S.;
RT   "An ionizing radiation-sensitive mutant of CHO cells: irs-20. III.
RT   Chromosome aberrations, DNA breaks and mitotic delay.";
RL   Int. J. Radiat. Biol. 65:571-582(1994).
//
RX   PubMed=8248482; DOI=10.2307/3578618;
RA   Stackhouse M.A., Bedford J.S.;
RT   "An ionizing radiation-sensitive mutant of CHO cells: irs-20. II.
RT   Dose-rate effects and cellular recovery processes.";
RL   Radiat. Res. 136:250-254(1993).
//
RX   PubMed=9008208; DOI=10.2307/3579417;
RA   Lin J.Y.-D., Muhlmann-Diaz M.C., Stackhouse M.A., Robinson J.F.,
RA   Taccioli G.E., Chen D.J., Bedford J.S.;
RT   "An ionizing radiation-sensitive CHO mutant cell line: irs-20. IV.
RT   Genetic complementation, V(D)J recombination and the scid phenotype.";
RL   Radiat. Res. 147:166-171(1997).
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RX   PubMed=9518490; DOI=10.1093/nar/26.8.1965; PMCID=PMC147487;
RA   Priestley A., Beamish H.J., Gell D., Amatucci A.G.,
RA   Muhlmann-Diaz M.C., Singleton B.K., Smith G.C.M., Blunt T.,
RA   Schalkwyk L.C., Bedford J.S., Jackson S.P., Jeggo P.A.,
RA   Taccioli G.E.;
RT   "Molecular and biochemical characterisation of DNA-dependent protein
RT   kinase-defective rodent mutant irs-20.";
RL   Nucleic Acids Res. 26:1965-1973(1998).
//