ID   OVCAR-3 SimpleCell O-GalNAc
AC   CVCL_S033
SY   OVCAR-3 SimpleCell; OVCAR-3 SC
DR   cancercelllines; CVCL_S033
DR   Wikidata; Q54937006
RX   PubMed=23584533;
CC   Population: Caucasian.
CC   Characteristics: Cell engineered to produce only truncated GalNAc or NeuAc-alpha-2-6-GalNAc O-glycans.
CC   Knockout cell: Method=ZFN; HGNC; 24338; C1GALT1C1.
CC   Sequence variation: Mutation; HGNC; 8979; PIK3R1; Simple; c.1746-2A>T; Zygosity=Heterozygous; Note=Splice acceptor mutation (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (from parent cell line).
CC   Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
DI   NCIt; C105555; High grade ovarian serous adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0465 ! OVCAR-3
SX   Female
AG   60Y
CA   Cancer cell line
DT   Created: 05-11-13; Last updated: 05-10-23; Version: 18
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RX   PubMed=23584533; DOI=10.1038/emboj.2013.79;
RA   Steentoft C., Vakhrushev S.Y., Joshi H.J., Kong Y.,
RA   Vester-Christensen M.B., Schjoldager K.T.-B.G., Lavrsen K.,
RA   Dabelsteen S., Pedersen N.B., Marcos-Silva L., Gupta R., Bennett E.P.,
RA   Mandel U., Brunak S., Wandall H.H., Levery S.B., Clausen H.;
RT   "Precision mapping of the human O-GalNAc glycoproteome through
RT   SimpleCell technology.";
RL   EMBO J. 32:1478-1488(2013).
//