ID   MCF-7 SimpleCell O-GalNAc
AC   CVCL_S030
SY   MCF-7 SimpleCell; MCF-7 SC
DR   cancercelllines; CVCL_S030
DR   Wikidata; Q54904326
RX   PubMed=23584533;
CC   Population: Caucasian.
CC   Characteristics: Cell engineered to produce only truncated GalNAc or NeuAc-alpha-2-6-GalNAc O-glycans.
CC   Knockout cell: Method=ZFN; HGNC; 24338; C1GALT1C1.
CC   Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C4194; Invasive breast carcinoma of no special type
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0031 ! MCF-7
SX   Female
AG   69Y
CA   Cancer cell line
DT   Created: 05-11-13; Last updated: 05-10-23; Version: 20
//
RX   PubMed=23584533; DOI=10.1038/emboj.2013.79; PMCID=PMC3655468;
RA   Steentoft C., Vakhrushev S.Y., Joshi H.J., Kong Y.,
RA   Vester-Christensen M.B., Schjoldager K.T.-B.G., Lavrsen K.,
RA   Dabelsteen S., Pedersen N.B., Marcos-Silva L., Gupta R., Bennett E.P.,
RA   Mandel U., Brunak S., Wandall H.H., Levery S.B., Clausen H.;
RT   "Precision mapping of the human O-GalNAc glycoproteome through
RT   SimpleCell technology.";
RL   EMBO J. 32:1478-1488(2013).
//