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Cellosaurus HEK293-YFV-prM/E-opt (CVCL_RZ86)

[Text version]
Cell line name HEK293-YFV-prM/E-opt
Accession CVCL_RZ86
Resource Identification Initiative To cite this cell line use: HEK293-YFV-prM/E-opt (RRID:CVCL_RZ86)
Comments Characteristics: Expresses the YFV prM/E proteins and capable of trans-packaging the transcribed RNA of a YFV reporter replicon, thereby generating pseudo-infectious viral particles.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03314; Yellow fever virus (strain 17D vaccine) genome polyprotein (Note=AA 102-778; protein prM + protein E, codons optimized for expression).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0045 (HEK293)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=29513845; DOI=10.1590/0037-8682-0220-2017
de Almeida Queiroz S.R., Silva J.V.J. Jr., da Silva A.N.M.R., de Oliveira Carvalho A.G., da Silva Santos J.J., Gil L.H.V.G.
Development and characterization of a packaging cell line for pseudo-infectious yellow fever virus particle generation.
Rev. Soc. Bras. Med. Trop. 51:66-70(2018)

Cross-references
Encyclopedic resources Wikidata; Q54882461
Entry history
Entry creation14-May-2018
Last entry update19-Dec-2024
Version number8