Cellosaurus Dox-pDC (CVCL_RX86)
| Cell line name | Dox-pDC |
|---|---|
| Synonyms | Doxycycline-inducible plasmacytoid Dendritic Cells |
| Accession | CVCL_RX86 |
| Resource Identification Initiative | To cite this cell line use: Dox-pDC (RRID:CVCL_RX86) |
| Comments | Characteristics: Stably proliferates by doxycycline-induction of the expression of the SV40 large T antigen. After withdrawal of doxycycline will stop proliferate and will undergo apoptosis within 3 days. Doubling time: 2.4 +- 0.3 days (PubMed=29489861). Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; SV40 large T antigen. Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40). Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371. Cell type: Plasmacytoid dendritic cell; CL=CL_0000784. |
| Species of origin | Mus musculus (Mouse)
(NCBI Taxonomy: 10090)
Breed/subspecies: Rosa-rtTA-flox-Tag+ transgenic. |
| Sex of cell | Female |
| Age at sampling | Age unspecified |
| Category | Conditionally immortalized cell line |
| Publications | PubMed=29489861; DOI=10.1371/journal.pone.0192437; PMCID=PMC5830289 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q54831364 |
| Entry history | |
| Entry creation | 05-Mar-2018 |
| Last entry update | 10-Sep-2024 |
| Version number | 7 |