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Cellosaurus AT1OS TERT (CVCL_RW89)

[Text version]
Cell line name AT1OS TERT
Synonyms AT1OS/TERT
Accession CVCL_RW89
Resource Identification Initiative To cite this cell line use: AT1OS TERT (RRID:CVCL_RW89)
Comments Population: Japanese.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; HGNC:795; ATM; Simple; c.4612del165 (Ex33del); Zygosity=Homozygous (from parent cell line).
Disease Ataxia telangiectasia syndrome (NCIt: C2887)
Ataxia telangiectasia (ORDO: Orphanet_100)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2860 (AT1OS)
Sex of cell Male
Age at sampling 10Y
Category Telomerase immortalized cell line
Publications

PubMed=14570874; DOI=10.1074/jbc.M309457200
Naka K., Tachibana A., Ikeda K., Motoyama N.
Stress-induced premature senescence in hTERT-expressing ataxia telangiectasia fibroblasts.
J. Biol. Chem. 279:2030-2037(2004)

Cross-references
Cell line collections (Providers) JCRB; KURB1768
Encyclopedic resources Wikidata; Q54750852
Entry history
Entry creation05-Mar-2018
Last entry update19-Dec-2024
Version number10