Cellosaurus cell line V79 SP5 (CVCL

Cellosaurus V79 SP5 (CVCL_RW41)

Cross-references
Cell line name	V79 SP5
Synonyms	V79 Sp5; V79/SP5; SP5; Sp5; SP5/V79
Accession	CVCL_RW41
Resource Identification Initiative	To cite this cell line use: V79 SP5 (RRID:CVCL_RW41)
Comments	Selected for resistance to: ChEBI; CHEBI:9555; Tioguanine (6-thioguanine; 6-TG). Derived from site: In situ; Lung; UBERON=UBERON_0002048. Cell type: Fibroblast of lung; CL=CL_0002553.
Sequence variations	Mutation; UniProtKB; P00494; Hprt1; Unexplicit; Ex2dup; Zygosity=Unspecified (PubMed=1576714). Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line). Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line).
Species of origin	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy	Parent: CVCL_2234 (V79)
Sex of cell	Male
Age at sampling	Adult
Category	Spontaneously immortalized cell line
Publications	PubMed=2471930; DOI=10.1016/0027-5107(89)90076-6 Zhang L.-H., Jenssen D. Isolation and characterization of spontaneously occurring mutations at the HPRT locus in V79 Chinese hamster cells. Mutat. Res. 212:253-262(1989) PubMed=1576714; DOI=10.1093/carcin/13.4.609 Zhang L.-H., Jenssen D. Reversion of the hprt mutant clone SP5 by intrachromosomal recombination. Carcinogenesis 13:609-615(1992) PubMed=7955071; DOI=10.1093/carcin/15.10.2303 Zhang L.-H., Jenssen D. Studies on intrachromosomal recombination in SP5/V79 Chinese hamster cells upon exposure to different agents related to carcinogenesis. Carcinogenesis 15:2303-2310(1994) PubMed=8914605; DOI=10.1007/BF02369910 Dare E., Zhang L.-H., Jenssen D. Characterization of mutants involving partial exon duplications in the hprt gene of Chinese hamster V79 cells. Somat. Cell Mol. Genet. 22:201-210(1996)
Encyclopedic resources	Wikidata; Q54992579
Entry history
Entry creation	05-Mar-2018
Last entry update	29-Jun-2023
Version number	9