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Cellosaurus WAe001-A-18 (CVCL_RV18)

[Text version]
Cell line name WAe001-A-18
Synonyms H1-p53(R282W/R282W); 1R5; CDMLe003-A; CDMLe004-A-18
Accession CVCL_RV18
Resource Identification Initiative To cite this cell line use: WAe001-A-18 (RRID:CVCL_RV18)
Comments From: Cancer Disease Modeling Laboratory, University of Texas Health Center at Houston; Houston; USA.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple_edited; p.Arg282Trp (c.844C>T); ClinVar=VCV000012364; Zygosity=Homozygous; Note=By TALEN (PubMed=29414603).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_9771 (WA01)
Sex of cell Male
Age at sampling Blastocyst stage
Category Embryonic stem cell
Publications

PubMed=29414603; DOI=10.1016/j.scr.2018.01.035
Zhou R.-J., Xu A., Wang D.-H., Zhu D.-D., Mata H., Huo Z.-J., Tu J., Liu M., Mohamed A.M.T., Jewell B.E., Gingold J.A., Xia W.-Y., Rao P.H., Hung M.-C., Zhao R.-Y., Lee D.-F.
A homozygous p53 R282W mutant human embryonic stem cell line generated using TALEN-mediated precise gene editing.
Stem Cell Res. 27:131-135(2018)

Cross-references
Cell line databases/resources hPSCreg; WAe001-A-18
Encyclopedic resources Wikidata; Q54993545
Entry history
Entry creation05-Mar-2018
Last entry update29-Jun-2023
Version number10