ID   BT048
AC   CVCL_RU29
SY   BT48; BT-48
DR   GEO; GSM2155021
DR   GEO; GSM2155024
DR   Wikidata; Q54798481
RX   PubMed=19544433;
RX   PubMed=20388696;
RX   PubMed=20593219;
RX   PubMed=26095605;
RX   PubMed=26245525;
CC   Group: Cancer stem cell line.
CC   Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (PubMed=26095605).
CC   Omics: Transcriptome analysis by microarray.
CC   Omics: Transcriptome analysis by RNAseq.
CC   Derived from site: In situ; Brain; UBERON=UBERON_0000955.
DI   NCIt; C3058; Glioblastoma
DI   ORDO; Orphanet_360; Glioblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   68Y
CA   Cancer cell line
DT   Created: 05-03-18; Last updated: 29-06-23; Version: 8
//
RX   PubMed=19544433; DOI=10.1002/stem.98;
RA   Kelly J.J.P., Stechishin O.D.M., Chojnacki A., Lun X.-Q., Sun B.-C.,
RA   Senger D.L., Forsyth P., Auer R.N., Dunn J.F., Cairncross J.G.,
RA   Parney I.F., Weiss S.;
RT   "Proliferation of human glioblastoma stem cells occurs independently
RT   of exogenous mitogens.";
RL   Stem Cells 27:1722-1733(2009).
//
RX   PubMed=20388696; DOI=10.1093/neuonc/noq031;
RA   Kelly J.J.P., Blough M.D., Stechishin O.D.M., Chan J.A.W.,
RA   Beauchamp D.C., Perizzolo M., Demetrick D.J., Steele L., Auer R.N.,
RA   Hader W.J., Westgate M.R., Parney I.F., Jenkins R.B., Cairncross J.G.,
RA   Weiss S.;
RT   "Oligodendroglioma cell lines containing t(1;19)(q10;p10).";
RL   Neuro-oncol. 12:745-755(2010).
//
RX   PubMed=20593219; DOI=10.1007/s11060-010-0283-9;
RA   Blough M.D., Beauchamp D.C., Westgate M.R., Kelly J.J.P.,
RA   Cairncross J.G.;
RT   "Effect of aberrant p53 function on temozolomide sensitivity of glioma
RT   cell lines and brain tumor initiating cells from glioblastoma.";
RL   J. Neurooncol. 102:1-7(2011).
//
RX   PubMed=26095605; DOI=10.1016/j.stemcr.2015.05.010;
RA   Cusulin C., Chesnelong C., Bose P., Bilenky M., Kopciuk K., Chan J.A.W.,
RA   Cairncross J.G., Jones S.J.M., Marra M.A., Luchman H.A., Weiss S.;
RT   "Precursor states of brain tumor initiating cell lines are predictive
RT   of survival in xenografts and associated with glioblastoma
RT   subtypes.";
RL   Stem Cell Reports 5:1-9(2015).
//
RX   PubMed=26245525; DOI=10.1093/neuonc/nov143;
RA   Davis B., Shen Y.-Q., Poon C.C., Luchman H.A., Stechishin O.D.M.,
RA   Pontifex C.S., Wu W., Kelly J.J.P., Blough M.D.;
RT   "Comparative genomic and genetic analysis of glioblastoma-derived
RT   brain tumor-initiating cells and their parent tumors.";
RL   Neuro-oncol. 18:350-360(2016).
//