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Cellosaurus SK-MEL-3rDACARB20 (CVCL_RS86)

[Text version]
Cell line name SK-MEL-3rDACARB20
Accession CVCL_RS86
Resource Identification Initiative To cite this cell line use: SK-MEL-3rDACARB20 (RRID:CVCL_RS86)
Comments Part of: Resistant Cancer Cell Line (RCCL) collection.
Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:4305; Dacarbazine (DTIC; (5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide)).
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000027.
Sequence variations
  • Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg267Trp (c.799C>T); ClinVar=VCV000141764; Zygosity=Homozygous (from parent cell line).
Disease Cutaneous melanoma (NCIt: C3510)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0550 (SK-MEL-3)
Sex of cell Female
Age at sampling 42Y
Category Cancer cell line
Web pages https://www.wass-michaelislab.org/rccl.php
Cell line databases/resources cancercelllines; CVCL_RS86
Encyclopedic resources Wikidata; Q54954149
Entry history
Entry creation05-Mar-2018
Last entry update05-Oct-2023
Version number10