Cellosaurus logo
expasy logo

Cellosaurus HELrARA-C2mug/ML (CVCL_RS48)

[Text version]
Cell line name HELrARA-C2mug/ML
Accession CVCL_RS48
Resource Identification Initiative To cite this cell line use: HELrARA-C2mug/ML (RRID:CVCL_RS48)
Comments Part of: Resistant Cancer Cell Line (RCCL) collection.
Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:28680; Cytarabine (Arabinosylcytosine; Ara-C).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Mutation; HGNC; 6192; JAK2; Simple; p.Val617Phe (c.1849G>T); ClinVar=VCV000014662; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Met133Lys (c.398T>A); ClinVar=VCV002430159; Zygosity=Homozygous (from parent cell line).
Disease Erythroleukemia (NCIt: C7152)
Acute erythroid leukemia (ORDO: Orphanet_318)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0001 (HEL)
Sex of cell Male
Age at sampling 30Y
Category Cancer cell line
Web pages https://www.wass-michaelislab.org/rccl.php
Cell line databases/resources cancercelllines; CVCL_RS48
Encyclopedic resources Wikidata; Q54882744
Entry history
Entry creation05-Mar-2018
Last entry update05-Oct-2023
Version number11