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Cellosaurus EMT6-LM2 (CVCL_RS43)

[Text version]
Cell line name EMT6-LM2
Synonyms EMT6-Lung Metastasis passage 2
Accession CVCL_RS43
Resource Identification Initiative To cite this cell line use: EMT6-LM2 (RRID:CVCL_RS43)
Comments Characteristics: Established from parent cell line by two passages in nude mice from spontaneous lung metastases following subcutaneous growth.
Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
Disease Malignant neoplasms of the mouse mammary gland (NCIt: C21678)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: BALB/cCRGL.
Hierarchy Parent: CVCL_1923 (EMT6)
Sex of cell Female
Category Cancer cell line
Publications

PubMed=29467918; DOI=10.18632/oncotarget.23795; PMCID=PMC5805504
Yingling J.M., McMillen W.T., Yan L., Huang H., Sawyer J.S., Graff J., Clawson D.K., Britt K.S., Anderson B.D., Beight D.W., Desaiah D., Lahn M.M., Benhadji K.A., Lallena M.J., Holmgaard R.B., Xu X.-H., Zhang F.-M., Manro J.R., Iversen P.W., Iyer C.V., Brekken R.A., Kalos M.D., Driscoll K.E.
Preclinical assessment of galunisertib (LY2157299 monohydrate), a first-in-class transforming growth factor-beta receptor type I inhibitor.
Oncotarget 9:6659-6677(2018)

Cross-references
Encyclopedic resources Wikidata; Q54832295
Entry history
Entry creation05-Mar-2018
Last entry update05-Oct-2023
Version number5