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Cellosaurus 22RV1rYM155_300nM (CVCL_RS39)

[Text version]
Cell line name 22RV1rYM155_300nM
Synonyms 22RV1rYM155(300nM)
Accession CVCL_RS39
Resource Identification Initiative To cite this cell line use: 22RV1rYM155_300nM (RRID:CVCL_RS39)
Comments Part of: Resistant Cancer Cell Line (RCCL) collection.
Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_139608; Sepantronium bromide (YM155).
Derived from site: In situ; Prostate; UBERON=UBERON_0002367.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Leu597Arg (c.1790T>G); ClinVar=VCV000013968; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7133; KMT2D; Simple; p.Arg1252Ter (c.3754C>T); ClinVar=VCV000167228; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7133; KMT2D; Simple; p.Gln3158Ter (c.9472C>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Gln546Arg (c.1637A>G); ClinVar=VCV000045466; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gln331Arg (c.992A>G); ClinVar=VCV000421319; Zygosity=Heterozygous (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1045 (22Rv1)
Sex of cell Male
Age at sampling Adult
Category Cancer cell line
Web pages https://www.wass-michaelislab.org/rccl.php
Cross-references
Cell line databases/resources cancercelllines; CVCL_RS39
Encyclopedic resources Wikidata; Q54583385
Entry history
Entry creation05-Mar-2018
Last entry update19-Dec-2024
Version number13