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Cellosaurus EFO-27rCDDP2000 (CVCL_RS28)

[Text version]
Cell line name EFO-27rCDDP2000
Accession CVCL_RS28
Resource Identification Initiative To cite this cell line use: EFO-27rCDDP2000 (RRID:CVCL_RS28)
Comments Part of: Resistant Cancer Cell Line (RCCL) collection.
Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:27899; Cisplatin (CDDP).
Derived from site: Metastatic; Omentum; UBERON=UBERON_0003688.
Sequence variations
  • Mutation; HGNC; 9588; PTEN; Simple; p.Lys267Argfs*9 (c.800delA) (p.Leu265fs, c.795delA); ClinVar=VCV000092828; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg273Cys (c.817C>T); ClinVar=VCV000043594; Zygosity=Heterozygous (from parent cell line).
Disease Ovarian mucinous adenocarcinoma (NCIt: C5243)
Mucinous adenocarcinoma of ovary (ORDO: Orphanet_398961)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1192 (EFO-27)
Sex of cell Female
Age at sampling 36Y
Category Cancer cell line
Web pages https://www.wass-michaelislab.org/rccl.php
Cell line databases/resources cancercelllines; CVCL_RS28
Encyclopedic resources Wikidata; Q54832068
Entry history
Entry creation05-Mar-2018
Last entry update05-Oct-2023
Version number11