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Cellosaurus SK-N-ASrOXALI4000 (CVCL_RR29)

[Text version]
Cell line name SK-N-ASrOXALI4000
Accession CVCL_RR29
Resource Identification Initiative To cite this cell line use: SK-N-ASrOXALI4000 (RRID:CVCL_RR29)
Comments Part of: Resistant Cancer Cell Line (RCCL) collection.
Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_31941; Oxaliplatin (Elotaxin; L-OHP).
Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1700 (SK-N-AS)
Sex of cell Female
Age at sampling 6Y
Category Cancer cell line
STR profile Source(s): PubMed=28192521

Markers:
AmelogeninX
CSF1PO10,12
D5S81811,12
D7S82011,13
D13S3179
D16S53914
TH019.3
TPOX11,12
vWA16,17

Run an STR similarity search on this cell line
Web pages Provider; RCCL; -; https://www.wass-michaelislab.org/rccl.php
Publications

PubMed=28192521; DOI=10.1371/journal.pone.0172140; PMCID=PMC5305101
Emily Saintas, Liam Abrahams, Gulshan T. Ahmad, Anu-Oluwa M. Ajakaiye, Abdulaziz S.H.A.M. AlHumaidi, Candice Ashmore-Harris, Iain Clark, Usha K. Dura, Carine N. Fixmer, Chinedu Ike-Morris, Mireia Mato Prado ...Show all 40 authors... , Danielle McCullough, Shishir Mishra, Katia M.U. Scholer, Husne Timur, Maxwell D.C. Williamson, Markella Alatsatianos, Basma Bahsoun, Edith Blackburn, Catherine E.M. Hogwood, Pamela E. Lithgow, Michelle Rowe, Lyto Yiangou, Florian Rothweiler, Jindrich Cinatl Jr., Richard Zehner, Anthony J. Baines, Michelle D. Garrett, Campbell W. Gourlay, Darren Karl Griffin, William J. Gullick, Emma Hargreaves, Mark J. Howard, Daniel R. Lloyd, Jeremy S. Rossman, Christopher Mark Smales, Anastasios D. Tsaousis, Tobias von der Haar, Mark N. Wass, Martin Michaelis; Show fewer authors
Acquired resistance to oxaliplatin is not directly associated with increased resistance to DNA damage in SK-N-ASrOXALI4000, a newly established oxaliplatin-resistant sub-line of the neuroblastoma cell line SK-N-AS.
PLoS ONE 12:e0172140.1-e0172140.17(2017)

Cross-references
Cell line databases/resources cancercelllines; CVCL_RR29
Encyclopedic resources Wikidata; Q54954430
Entry history
Entry creation05-Mar-2018
Last entry update10-Apr-2025
Version number14