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Cellosaurus SK-N-ASrOXALI4000 (CVCL_RR29)

[Text version]
Cell line name SK-N-ASrOXALI4000
Accession CVCL_RR29
Resource Identification Initiative To cite this cell line use: SK-N-ASrOXALI4000 (RRID:CVCL_RR29)
Comments Part of: Resistant Cancer Cell Line (RCCL) collection.
Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:31941; Oxaliplatin (Elotaxin; L-OHP).
Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1700 (SK-N-AS)
Sex of cell Female
Age at sampling 6Y
Category Cancer cell line
STR profile Source(s): PubMed=28192521


Run an STR similarity search on this cell line
Web pages https://www.wass-michaelislab.org/rccl.php

PubMed=28192521; DOI=10.1371/journal.pone.0172140
Saintas E., Abrahams L., Ahmad G.T., Ajakaiye A.-O.M., AlHumaidi A.S.H.A.M., Ashmore-Harris C., Clark I., Dura U.K., Fixmer C.N., Ike-Morris C., Mato Prado M., McCullough D., Mishra S., Scholer K.M.U., Timur H., Williamson M.D.C., Alatsatianos M., Bahsoun B., Blackburn E., Hogwood C.E., Lithgow P.E., Rowe M., Yiangou L., Rothweiler F., Cinatl J. Jr., Zehner R., Baines A.J., Garrett M.D., Gourlay C.W., Griffin D.K., Gullick W.J., Hargreaves E., Howard M.J., Lloyd D.R., Rossman J.S., Smales C.M., Tsaousis A.D., von der Haar T., Wass M.N., Michaelis M.
Acquired resistance to oxaliplatin is not directly associated with increased resistance to DNA damage in SK-N-ASrOXALI4000, a newly established oxaliplatin-resistant sub-line of the neuroblastoma cell line SK-N-AS.
PLoS ONE 12:E0172140-E0172140(2017)

Cell line databases/resources cancercelllines; CVCL_RR29
Encyclopedic resources Wikidata; Q54954430
Entry history
Entry creation05-Mar-2018
Last entry update05-Oct-2023
Version number12