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Cellosaurus B3 HA-159A Ikaros-IRES-GFP (CVCL_RP58)

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Cell line name B3 HA-159A Ikaros-IRES-GFP
Accession CVCL_RP58
Resource Identification Initiative To cite this cell line use: B3 HA-159A Ikaros-IRES-GFP (RRID:CVCL_RP58)
Comments Characteristics: Transfected with a fusion protein of hemagglutinin-tagged wildtype Ikaros (HA-Ikaros) and the estrogen receptor hormone-binding domain (ERt2), followed by an internal ribosomal entry site (IRES) and GFP.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:13176; IKZF1 (Note=With p.Asn159Ala).
Genetic integration: Method=Transfection; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transgenic mouse; Gene=MGI; MGI:96561; Il7.
Omics: Transcriptome analysis by microarray.
Disease Mouse lymphoma (NCIt: C21602)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: 10-III-42 transgenic Tg(H2-Ea-Il7)10Rhdr.
Hierarchy Parent: CVCL_RP56 (B3)
Category Cancer cell line
Publications

PubMed=23303821; DOI=10.1182/blood-2012-08-450114
Ferreiros-Vidal I., Carroll T., Taylor B., Terry A., Liang Z.-W., Bruno L., Dharmalingam G., Khadayate S., Cobb B.S., Smale S.T., Spivakov M., Srivastava P., Petretto E., Fisher A.G., Merkenschlager M.
Genome-wide identification of Ikaros targets elucidates its contribution to mouse B-cell lineage specification and pre-B-cell differentiation.
Blood 121:1769-1782(2013)

Cross-references
Encyclopedic resources Wikidata; Q54752597
Gene expression databases GEO; GSM934760
GEO; GSM934761
Entry history
Entry creation05-Mar-2018
Last entry update19-Dec-2024
Version number6