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Cellosaurus T24T FL4 (CVCL_RN62)

[Text version]
Cell line name T24T FL4
Synonyms FL4
Accession CVCL_RN62
Resource Identification Initiative To cite this cell line use: T24T FL4 (RRID:CVCL_RN62)
Comments Population: Caucasian; Swedish.
Characteristics: Forms metastasis in the lung of mice. Produced by passage of the parent cell line through nude mice.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Sequence variations
  • Mutation; HGNC; HGNC:5173; HRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012600; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr126Ter (c.378C>G); ClinVar=VCV000578988; Zygosity=Homozygous (from parent cell line).
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_M897 (T24T FL3)
Sex of cell Female
Age at sampling 82Y
Category Cancer cell line
Publications

PubMed=19147813; DOI=10.2353/ajpath.2009.080538; PMCID=PMC2630547
Smith S.C., Nicholson B., Nitz M.D., Frierson H.F. Jr., Smolkin M., Hampton G.M., El-Rifai W., Theodorescu D.
Profiling bladder cancer organ site-specific metastasis identifies LAMC2 as a novel biomarker of hematogenous dissemination.
Am. J. Pathol. 174:371-379(2009)

Cross-references
Cell line databases/resources cancercelllines; CVCL_RN62
Encyclopedic resources Wikidata; Q54971473
Entry history
Entry creation05-Mar-2018
Last entry update19-Dec-2024
Version number12