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Cellosaurus CHOZN GS-/- Slc35a1-/- (CVCL_RN11)

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Cell line name CHOZN GS-/- Slc35a1-/-
Synonyms SLC35A1 KO CHO
Accession CVCL_RN11
Resource Identification Initiative To cite this cell line use: CHOZN GS-/- Slc35a1-/- (RRID:CVCL_RN11)
Comments Group: Serum/protein free medium cell line.
Virology: Resistant to infection/contamination by minute virus of mice (MVM).
Knockout cell: Method=ZFN; UniProtKB; P04773; Glul.
Knockout cell: Method=ZFN; UniProtKB; O08520; Slc35a1.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_RN03 (CHOZN GS-/-)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Web pages https://www.sigmaaldrich.com/technical-documents/articles/biology/mvm-resistance-through-genetic-engineering.html

PubMed=27642072; DOI=10.1002/bit.26186
Mascarenhas J.X., Korokhov N., Burger L., Kassim A., Tuter J., Miller D., Borgschulte T., George H.J., Chang A., Pintel D.J., Onions D.E., Kayser K.J.
Genetic engineering of CHO cells for viral resistance to minute virus of mice.
Biotechnol. Bioeng. 114:576-588(2017)

Lin N., Mascarenhas J.X., Chang A., Onions D.E., George H.J., Kayser K.J.
Viral resistant cells and uses thereof.
Patent number US10377990, 13-Aug-2019

Encyclopedic resources Wikidata; Q54813256
Entry history
Entry creation05-Mar-2018
Last entry update29-Jun-2023
Version number7