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Cellosaurus PDIS-2 (CVCL_RN07)

[Text version]
Cell line name PDIS-2
Synonyms HEK-293T/hPDPN-knockout; HEK-293T/hPDPN-KO
Accession CVCL_RN07
Resource Identification Initiative To cite this cell line use: PDIS-2 (RRID:CVCL_RN07)
Comments Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:29602; PDPN.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA).
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0063 (HEK293T)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=26937552; DOI=10.1089/mab.2015.0077
Kato Y., Ogasawara S., Oki H., Honma R., Takagi M., Fujii Y., Nakamura T., Saidoh N., Kanno H., Umetsu M., Kamata S., Kubo H., Yamada M., Sawa Y., Morita K.-i., Harada H., Suzuki H., Kaneko M.K.
Novel monoclonal antibody LpMab-17 developed by CasMab technology distinguishes human podoplanin from monkey podoplanin.
Monoclon. Antib. Immunodiagn. Immunother. 35:109-116(2016)

PubMed=27031228; DOI=10.1371/journal.pone.0152912; PMCID=PMC4816300
Kato Y., Ogasawara S., Oki H., Goichberg P., Honma R., Fujii Y., Kaneko M.K.
LpMab-12 established by CasMab technology specifically detects sialylated O-glycan on Thr52 of platelet aggregation-stimulating domain of human podoplanin.
PLoS ONE 11:E0152912-E0152912(2016)

PubMed=27328060; DOI=10.1089/mab.2016.0006
Ogasawara S., Kaneko M.K., Honma R., Oki H., Fujii Y., Takagi M., Suzuki H., Kato Y.
Establishment of mouse monoclonal antibody LpMab-13 against human podoplanin.
Monoclon. Antib. Immunodiagn. Immunother. 35:155-162(2016)

PubMed=27564251; DOI=10.1089/mab.2016.0031
Ogasawara S., Kaneko M.K., Kato Y.
LpMab-19 recognizes sialylated O-Glycan on Thr76 of human podoplanin.
Monoclon. Antib. Immunodiagn. Immunother. 35:245-253(2016)

PubMed=28101903; DOI=10.1002/cam4.954; PMCID=PMC5313638
Kaneko M.K., Nakamura T., Honma R., Ogasawara S., Fujii Y., Abe S., Takagi M., Harada H., Suzuki H., Nishioka Y., Kato Y.
Development and characterization of anti-glycopeptide monoclonal antibodies against human podoplanin, using glycan-deficient cell lines generated by CRISPR/Cas9 and TALEN.
Cancer Med. 6:382-396(2017)

Cross-references
Encyclopedic resources Wikidata; Q54946846
Entry history
Entry creation05-Mar-2018
Last entry update19-Dec-2024
Version number10