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Cellosaurus Z-HL16C (CVCL_RL03)

[Text version]
Cell line name Z-HL16C
Synonyms ZHL16C
Accession CVCL_RL03
Resource Identification Initiative To cite this cell line use: Z-HL16C (RRID:CVCL_RL03)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=26116706). Originally thought to originate from embryonic lung fibroblasts.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00609.
Population: African American.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
STR profile Source(s): PubMed=26116706

Markers:
AmelogeninX
CSF1PO9,10
D2S133817
D3S135815,18
D5S81811,12
D6S104318
D7S8208,12
D8S117912,13
D12S39120,25
D13S31713.3
D16S5399,10
D18S5116,17
D19S43313,14
D21S1127,28
FGA18,21
Penta D8,15
Penta E7,17
TH017
TPOX8,12
vWA16,18

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Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx
Publications

PubMed=11503031; DOI=10.3760/cma.j.issn.1003-9279.2000.01.017
Zhao S.-L., Liu Z.-L., Xie R.-N.
Establishment and application of Z-HL16C cell line.
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 14:73-76(2000)

PubMed=17086279; DOI=10.3760/cma.j.issn.1003-9279.2006.03.010
Chen J.-P., Li J., Zhao S.-L., Tian J.-Y., Ye F.
Establishment of Z-HL16C cell line.
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 20:232-234(2006)

PubMed=26116706; DOI=10.1096/fj.14-266718
Ye F., Chen C.-G., Qin J., Liu J., Zheng C.-Y.
Genetic profiling reveals an alarming rate of cross-contamination among human cell lines used in China.
FASEB J. 29:4268-4272(2015)

Cross-references
Encyclopedic resources Wikidata; Q54995852
Entry history
Entry creation05-Mar-2018
Last entry update05-Oct-2023
Version number9