ID   SU042-4
AC   CVCL_RK76
DR   SKIP; SKIP001717
DR   Wikidata; Q54970753
RX   PubMed=28089908;
CC   Sequence variation: Mutation; HGNC; HGNC:795; ATM; Simple; p.Val2193Ile (c.6577G>A); ClinVar=VCV000231987; Zygosity=Unspecified; Note=Somatic (PubMed=28089908).
CC   Sequence variation: Mutation; HGNC; HGNC:2978; DNMT3A; Simple; p.Ser837Ter (c.2510C>G); Zygosity=Unspecified; Note=Somatic (PubMed=28089908).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly13Asp (c.38G>A); ClinVar=VCV000012580; Zygosity=Unspecified; Note=Somatic (PubMed=28089908).
CC   Sequence variation: Mutation; HGNC; HGNC:30045; SMG1; Simple; p.Leu250Val; Zygosity=Unspecified; Note=Somatic (PubMed=28089908).
CC   Sequence variation: Mutation; HGNC; HGNC:17575; SPEN; Simple; p.Thr1673Ser; Zygosity=Unspecified; Note=Somatic (PubMed=28089908).
DI   NCIt; C9154; Adult acute myeloid leukemia
DI   ORDO; Orphanet_519; Acute myeloid leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_RK73 ! SU042-1
OI   CVCL_RK74 ! SU042-2
OI   CVCL_RK75 ! SU042-3
OI   CVCL_RK77 ! SU042-5
OI   CVCL_RK78 ! SU42T-2
OI   CVCL_RK79 ! SU42T-4
OI   CVCL_RK80 ! SU42T-5
SX   Female
AG   61Y
CA   Induced pluripotent stem cell
DT   Created: 05-03-18; Last updated: 19-12-24; Version: 9
//
RX   PubMed=28089908; DOI=10.1016/j.stem.2016.11.018; PMCID=PMC5508733;
RA   Chao M.P., Gentles A.J., Chatterjee S., Lan F., Reinisch A.,
RA   Corces M.R., Xavy S., Shen J.-F., Haag D., Chanda S., Sinha R.,
RA   Morganti R.M., Nishimura T., Ameen M., Wu H.-D., Wernig M., Wu J.C.,
RA   Majeti R.;
RT   "Human AML-iPSCs reacquire leukemic properties after differentiation
RT   and model clonal variation of disease.";
RL   Cell Stem Cell 20:329-344.e7(2017).
//