| Cell line name |
LNCaP-CL2 |
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| Synonyms |
CL2; CL-2 |
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| Accession |
CVCL_RK71 |
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| Resource Identification Initiative |
To cite this cell line use: LNCaP-CL2 (RRID:CVCL_RK71) |
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| Comments |
Population: Caucasian.
Derived from site: Metastatic; Left supraclavicular lymph node; UBERON=UBERON_8480056. |
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| Sequence variations |
- Mutation; HGNC; HGNC:644; AR; Simple; p.Thr878Ala (c.2632A>G); ClinVar=VCV000009831; Zygosity=Hemizygous (from parent cell line).
- Mutation; HGNC; HGNC:7010; MEN1; Simple; p.Tyr318Ter (c.954T>G) (p.Tyr313Ter, c.939T>A); ClinVar=VCV000439894; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:8979; PIK3R1; Simple; p.Arg639Ter (c.1915C>T); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Lys6Argfs*4 (c.17_18delAA); ClinVar=VCV000231649; Zygosity=Unspecified (from parent cell line).
|
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| Disease |
Prostate carcinoma (NCIt: C4863) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_3872 (LNCaP-CL1) |
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| Sex of cell |
Male |
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| Age at sampling |
50Y |
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| Category |
Cancer cell line |
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| Publications | PubMed=11038142
Tso C.-L., McBride W.H., Sun J.-R., Patel B.J., Tsui K.-H., Paik S.H., Gitlitz B., Caliliw R., van Ophoven A., Wu L., deKernion J.B., Belldegrun A.S.
Androgen deprivation induces selective outgrowth of aggressive hormone-refractory prostate cancer clones expressing distinct cellular and molecular properties not present in parental androgen-dependent cancer cells.
Cancer J. Sci. Am. 6:220-233(2000) |
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| Cross-references |
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| Cell line databases/resources |
cancercelllines; CVCL_RK71
|
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| Encyclopedic resources |
Wikidata; Q54902834
|
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| Entry history |
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| Entry creation | 05-Mar-2018 |
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| Last entry update | 19-Dec-2024 |
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| Version number | 11 |
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