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Cellosaurus HN-SCC-135 (CVCL_RK52)

[Text version]
Cell line name HN-SCC-135
Synonyms HNSCC 135
Accession CVCL_RK52
Resource Identification Initiative To cite this cell line use: HN-SCC-135 (RRID:CVCL_RK52)
Comments Derived from site: In situ; Oral cavity, hard palate; UBERON=UBERON_0003216.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Lys132Arg (c.395A>G); ClinVar=VCV000376625; Zygosity=Unspecified (PubMed=8339273).
Disease Oral cavity squamous cell carcinoma (NCIt: C4833)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=2394610; DOI=10.1016/0360-3016(90)90539-V
Weichselbaum R.R., Beckett M.A., Vijayakumar S., Simon M.A., Awan A.M., Nachman J., Panje W.R., Goldman M.E., Tybor A.G., Moran W.J., Vokes E.E., Ahmed-Swan S., Farhangi E.
Radiobiological characterization of head and neck and sarcoma cells derived from patients prior to radiotherapy.
Int. J. Radiat. Oncol. Biol. Phys. 19:313-319(1990)

PubMed=1574572; DOI=10.2307/3578273
Dunphy E.J., Beckett M.A., Thompson L.H., Weichselbaum R.R.
Expression of the polymorphic human DNA repair gene XRCC1 does not correlate with radiosensitivity in the cells of human head and neck tumor cell lines.
Radiat. Res. 130:166-170(1992)

PubMed=8339273
Brachman D.G., Beckett M.A., Graves D., Haraf D., Vokes E.E., Weichselbaum R.R.
p53 mutation does not correlate with radiosensitivity in 24 head and neck cancer cell lines.
Cancer Res. 53:3667-3669(1993)

DOI=10.1007/978-1-4615-2023-8_7
Weichselbaum R.R., Beckett M.A., Vokes E.E., Brachman D.G., Haraf D., Hallahan D.E., Kufe D.W.
Cellular and molecular mechanisms of radioresistance.
(In book chapter) Head and neck cancer. Cancer treatment and research, Vol. 74; Hong W.K., Weber R.S. (eds.); pp.131-140; Springer; Boston; USA (1995)

Cross-references
Cell line databases/resources cancercelllines; CVCL_RK52
Encyclopedic resources Wikidata; Q54890004
Polymorphism and mutation databases IARC_TP53; 6394
Entry history
Entry creation05-Mar-2018
Last entry update05-Oct-2023
Version number9