Cellosaurus cell line CLC13 (CVCL

Cellosaurus CLC13 (CVCL_RH19)

[Text version]

Cell line name

CLC13

Synonyms

Chinese Liver Cancer cell line 13

Accession

CVCL_RH19

Resource Identification Initiative

To cite this cell line use: CLC13 (RRID:CVCL_RH19)

Comments

Part of: Liver Cancer Model Repository (LIMORE).
Population: Chinese.
Transformant: NCBI_TaxID; 10407; Hepatitis B virus (HBV).
Omics: Genome sequenced.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.

Sequence variations

Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Thr41Ile (c.122C>T); ClinVar=VCV000017587; Zygosity=Unspecified (PubMed=31378681).
Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (PubMed=31378681).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly105Asp (c.314G>A); ClinVar=VCV000141114; Zygosity=Unspecified (PubMed=27273737; PubMed=31378681).

Disease

Adult hepatocellular carcinoma (NCIt: C7956)
Adult hepatocellular carcinoma (ORDO: Orphanet_210159)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Female

Age at sampling

64Y

Category

Cancer cell line

STR profile

Source(s): PubMed=27273737; PubMed=31378681

Markers:

Amelogenin	X
CSF1PO	11
D5S818	13
D7S820	10
D13S317	11,12
D16S539	12
TH01	8,9.3
TPOX	8,9
vWA	14,17

Publications

PubMed=27273737; DOI=10.1038/srep27411; PMCID=PMC4895220
Qiu Z.-X., Zou K.-K., Zhuang L.-P., Qin J.-J., Li H., Li C., Zhang Z.-T., Chen X.-T., Cen J., Meng Z.-Q., Zhang H.-B., Li Y.-X., Hui L.-J.
Hepatocellular carcinoma cell lines retain the genomic and transcriptomic landscapes of primary human cancers.
Sci. Rep. 6:27411-27411(2016)

PubMed=31378681; DOI=10.1016/j.ccell.2019.07.001; PMCID=PMC7505724
Qiu Z.-X., Li H., Zhang Z.-T., Zhu Z.-F., He S., Wang X.-J., Wang P.-C., Qin J.-J., Zhuang L.-P., Wang W., Xie F.-B., Gu Y., Zou K.-K., Li C., Li C., Wang C.-H., Cen J., Chen X.-T., Shu Y.-J., Zhang Z., Sun L.-L., Min L.-H., Fu Y., Huang X.-W., Lv H., Zhou H., Ji Y., Zhang Z.-G., Meng Z.-Q., Shi X.-L., Zhang H.-B., Li Y.-X., Hui L.-J.
A pharmacogenomic landscape in human liver cancers.
Cancer Cell 36:179-193.e11(2019)

Cross-references

Cell line databases/resources

cancercelllines; CVCL_RH19
LIMORE; CLC13

Encyclopedic resources

Wikidata; Q54813580

Gene expression databases

GEO; GSM2070050

Sequence databases

EGA; EGAS00001001678

Entry history

Entry creation

05-Mar-2018

Last entry update

19-Dec-2024

Version number