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Cellosaurus CLC4 (CVCL_RH14)

[Text version]
Cell line name CLC4
Synonyms Chinese Liver Cancer cell line 4
Accession CVCL_RH14
Resource Identification Initiative To cite this cell line use: CLC4 (RRID:CVCL_RH14)
Comments Part of: Liver Cancer Model Repository (LIMORE).
Population: Chinese.
Doubling time: 42.81 hours (PubMed=31378681).
Transformant: NCBI_TaxID; 10407; Hepatitis B virus (HBV).
Omics: Genome sequenced.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
Disease Adult hepatocellular carcinoma (NCIt: C7956)
Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 41Y
Category Cancer cell line
STR profile Source(s): PubMed=27273737; PubMed=31378681

Markers:
AmelogeninX,Y
CSF1PO10,12
D5S81811,12
D7S82011,12
D13S3179
D16S5399
TH016,9
TPOX8,12
vWA16,18

Run an STR similarity search on this cell line
Publications

PubMed=27273737; DOI=10.1038/srep27411; PMCID=PMC4895220
Qiu Z.-X., Zou K.-K., Zhuang L.-P., Qin J.-J., Li H., Li C., Zhang Z.-T., Chen X.-T., Cen J., Meng Z.-Q., Zhang H.-B., Li Y.-X., Hui L.-J.
Hepatocellular carcinoma cell lines retain the genomic and transcriptomic landscapes of primary human cancers.
Sci. Rep. 6:27411-27411(2016)

PubMed=31378681; DOI=10.1016/j.ccell.2019.07.001; PMCID=PMC7505724
Qiu Z.-X., Li H., Zhang Z.-T., Zhu Z.-F., He S., Wang X.-J., Wang P.-C., Qin J.-J., Zhuang L.-P., Wang W., Xie F.-B., Gu Y., Zou K.-K., Li C., Li C., Wang C.-H., Cen J., Chen X.-T., Shu Y.-J., Zhang Z., Sun L.-L., Min L.-H., Fu Y., Huang X.-W., Lv H., Zhou H., Ji Y., Zhang Z.-G., Meng Z.-Q., Shi X.-L., Zhang H.-B., Li Y.-X., Hui L.-J.
A pharmacogenomic landscape in human liver cancers.
Cancer Cell 36:179-193.e11(2019)

Cross-references
Cell line databases/resources cancercelllines; CVCL_RH14
LIMORE; CLC4
Encyclopedic resources Wikidata; Q54813583
Gene expression databases GEO; GSM2070038
Entry history
Entry creation05-Mar-2018
Last entry update19-Dec-2024
Version number11