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Cellosaurus GMA32 (CVCL_RG47)

[Text version]
Cell line name GMA32
Accession CVCL_RG47
Resource Identification Initiative To cite this cell line use: GMA32 (RRID:CVCL_RG47)
Comments Characteristics: Deoxycytidine kinase (dCK)-deficient.
Selected for resistance to: ChEBI; CHEBI_28680; Cytarabine (Arabinosylcytosine; Ara-C).
Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Cell type: Fibroblast of lung; CL=CL_0002553.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_2886 (Dede)
Children:
CVCL_C8BY (HC4)CVCL_C8BZ (HC5)CVCL_C8C0 (HC6)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=4359990; DOI=10.1111/j.1432-1033.1973.tb03009.x
Robert de Saint-Vincent B., Buttin G.
Studies on 1-beta-D-arabinofuranosyl-cytosine-resistant mutants of Chinese-hamster fibroblasts. A mitochondrial deoxycytidine kinase devoid of activity on arabino-cytosine.
Eur. J. Biochem. 37:481-488(1973)

PubMed=7162515; DOI=10.1128/mcb.2.11.1346-1353.1982; PMCID=PMC369939
Debatisse M., Berry M., Buttin G.
Stepwise isolation and properties of unstable Chinese hamster cell variants that overproduce adenylate deaminase.
Mol. Cell. Biol. 2:1346-1353(1982)

PubMed=6526013; DOI=10.1002/j.1460-2075.1984.tb02268.x; PMCID=PMC557827
Debatisse M., Robert de Saint-Vincent B., Buttin G.
Expression of several amplified genes in an adenylate-deaminase overproducing variant of Chinese hamster fibroblasts.
EMBO J. 3:3123-3127(1984)

PubMed=3785179; DOI=10.1128/mcb.6.5.1776-1781.1986; PMCID=PMC367706
Debatisse M., Hyrien O., Petit-Koskas E., Robert de Saint-Vincent B., Buttin G.
Segregation and rearrangement of coamplified genes in different lineages of mutant cells that overproduce adenylate deaminase.
Mol. Cell. Biol. 6:1776-1781(1986)

Cross-references
Encyclopedic resources Wikidata; Q54854286
Entry history
Entry creation05-Mar-2018
Last entry update19-Dec-2024
Version number7