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Cellosaurus MS-5-Omi/HTRA2-mCherry (CVCL_RG44)

[Text version]
Cell line name MS-5-Omi/HTRA2-mCherry
Synonyms MS-5 OMI/HTRA2-mCherry; MS-5-Omi-mCherry
Accession CVCL_RG44
Resource Identification Initiative To cite this cell line use: MS-5-Omi/HTRA2-mCherry (RRID:CVCL_RG44)
Comments Characteristics: The HTRA2-mCherry fusion protein is expressed in mitochondria inter-membrane space and is rapidly degraded following mitochondrial outer membrane permeabilization (MOMP).
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:14348; HTRA2.
Genetic integration: Method=Transfection/transduction; Gene=FPbase; ZERB6; mCherry (Note=Red fluorescent protein derived from drFP583 (dsRed)).
Transformant: NCIt; C17262; X-Ray.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C3H/HeNSlc.
Hierarchy Parent: CVCL_2128 (MS-5 [Mouse bone marrow])
Sex of cell Male
Age at sampling 8W
Category Stromal cell line
Web pages https://migratech.inserm-transfert.fr/srv/tech/2/0vue2.asp?n=606
Publications

PubMed=27257182; DOI=10.1182/blood-2015-07-655860
Moschoi R., Imbert V., Nebout M., Chiche J., Mary D., Prebet T., Saland E., Castellano R., Pouyet L., Collette Y., Vey N., Chabannon C., Recher C., Sarry J.-E., Alcor D., Peyron J.-F., Griessinger E.
Protective mitochondrial transfer from bone marrow stromal cells to acute myeloid leukemic cells during chemotherapy.
Blood 128:253-264(2016)

Cross-references
Encyclopedic resources Wikidata; Q54906773
Entry history
Entry creation05-Mar-2018
Last entry update19-Dec-2024
Version number10