Cellosaurus cell line STBCi025-A (CVCL

Cellosaurus STBCi025-A (CVCL_RB82)

Cross-references
Cell line name	STBCi025-A
Synonyms	SFC834-03-01
Accession	CVCL_RB82
Resource Identification Initiative	To cite this cell line use: STBCi025-A (RRID:CVCL_RB82)
Comments	From: StemBANCC; Oxford; United Kingdom. Cell type: Fibroblast; CL=CL_0000057.
Sequence variations	Mutation; HGNC; HGNC:4177; GBA1; Simple; p.Asn409Ser (c.1226A>G) (N370S); ClinVar=VCV000004290; Zygosity=Heterozygous (PubMed=26905200).
Disease	Parkinson's disease (NCIt: C26845) Hereditary late-onset Parkinson disease (ORDO: Orphanet_411602)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_RB83 ! STBCi025-B CVCL_RB84 ! STBCi025-C
Sex of cell	Male
Age at sampling	72Y
Category	Induced pluripotent stem cell
Publications	PubMed=26905200; DOI=10.1016/j.stemcr.2016.01.013; PMCID=PMC4788783 Fernandes H.J.R., Hartfield E.M., Christian H.C., Emmanoulidou E., Zheng Y., Booth H., Bogetofte H., Lang C., Ryan B.J., Sardi S.P., Badger J., Vowles J., Evetts S., Tofaris G.K., Vekrellis K., Talbot K., Hu M.T., James W., Cowley S.A., Wade-Martins R. ER stress and autophagic perturbations lead to elevated extracellular alpha-synuclein in GBA-N370S Parkinson's iPSC-derived dopamine neurons. Stem Cell Reports 6:342-356(2016)
Cell line collections (Providers)	EBiSC; STBCi025-A ECACC; 66540691 - Discontinued
Cell line databases/resources	hPSCreg; STBCi025-A
Biological sample resources	BioSamples; SAMEA104493656
Encyclopedic resources	Wikidata; Q54956405
Entry history
Entry creation	05-Mar-2018
Last entry update	19-Dec-2024
Version number	14