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Cellosaurus HPC-7 (CVCL_RB19)

[Text version]
Cell line name HPC-7
Synonyms HPC7; Hematopoietic precursor cell-7
Accession CVCL_RB19
Resource Identification Initiative To cite this cell line use: HPC-7 (RRID:CVCL_RB19)
Comments Characteristics: KITLG dependent.
Genetic integration: Method=Transfection/transduction; Gene=MGI; MGI:96785; Lhx2.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Breed/subspecies: 129S/SvEv-Gpi1<c>.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_C313 (CCE)
Sex of cell Male
Age at sampling Blastocyst stage
Category Factor-dependent cell line
Publications

PubMed=9755174; DOI=10.1093/emboj/17.19.5744; PMCID=PMC1170902
Pinto-do-O P., Kolterud A., Carlsson L.
Expression of the LIM-homeobox gene LH2 generates immortalized steel factor-dependent multipotent hematopoietic precursors.
EMBO J. 17:5744-5756(1998)

PubMed=19346495; DOI=10.1182/blood-2009-01-200048
Wilson N.K., Miranda-Saavedra D., Kinston S., Bonadies N., Foster S.D., Calero-Nieto F., Dawson M.A., Donaldson I.J., Dumon S., Frampton J., Janky R., Sun X.-H., Teichmann S.A., Bannister A.J., Gottgens B.
The transcriptional program controlled by the stem cell leukemia gene Scl/Tal1 during early embryonic hematopoietic development.
Blood 113:5456-5465(2009)

Cross-references
Encyclopedic resources Wikidata; Q54890250
Gene expression databases GEO; GSM397032
GEO; GSM397033
Entry history
Entry creation05-Mar-2018
Last entry update10-Sep-2024
Version number5