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Cellosaurus HPC-7 (CVCL_RB19)

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Cell line name HPC-7
Synonyms HPC7; Hematopoietic precursor cell-7
Accession CVCL_RB19
Resource Identification Initiative To cite this cell line use: HPC-7 (RRID:CVCL_RB19)
Comments Characteristics: KITLG dependent.
Genetic integration: Method=Transfection/transduction; Gene=MGI; MGI:96785; Lhx2.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Breed/subspecies: 129S/SvEv-Gpi1<c>.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_C313 (CCE)
Sex of cell Male
Age at sampling Blastocyst stage
Category Factor-dependent cell line
Publications

PubMed=9755174; DOI=10.1093/emboj/17.19.5744; PMCID=PMC1170902
Perpetua Pinto-do-O, Asa Kolterud, Leif Carlsson;
Expression of the LIM-homeobox gene LH2 generates immortalized steel factor-dependent multipotent hematopoietic precursors.
EMBO J. 17:5744-5756(1998)

PubMed=19346495; DOI=10.1182/blood-2009-01-200048
Nicola Kaye Wilson, Diego Miranda-Saavedra, Sarah Kinston, Nicolas Bonadies, Samuel D. Foster, Fernando Calero-Nieto, Mark A. Dawson, Ian J. Donaldson, Stephanie Dumon, Jonathan Frampton, Rekin's Janky ...Show all 15 authors... , Xiao-Hong Sun, Sarah Amalia Teichmann, Andrew J. Bannister, Berthold Gottgens; Show fewer authors
The transcriptional program controlled by the stem cell leukemia gene Scl/Tal1 during early embryonic hematopoietic development.
Blood 113:5456-5465(2009)

Cross-references
Encyclopedic resources Wikidata; Q54890250
Gene expression databases GEO; GSM397032
GEO; GSM397033
Entry history
Entry creation05-Mar-2018
Last entry update10-Sep-2024
Version number5