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Cellosaurus 2E2A6 (CVCL_RA98)

[Text version]
Cell line name 2E2A6
Accession CVCL_RA98
Resource Identification Initiative To cite this cell line use: 2E2A6 (RRID:CVCL_RA98)
Comments Group: Patented cell line.
Biotechnology: Used in a bioassay to measure botulinum toxin serotype A (BoNT/A) activity. Together with neuroblastoma cell line SiMa (Cellosaurus=CVCL_1695).
Monoclonal antibody isotype: IgG3, kappa.
Monoclonal antibody target: UniProtKB; P60880; Human SNAP25 (Note=With p.Arg198_Gly206del = SNAP25(197)).
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_4032 (P3X63Ag8.653)
Category Hybridoma
Publications

PubMed=23185348; DOI=10.1371/journal.pone.0049516; PMCID=PMC3504020
Fernandez-Salas E., Wang J., Molina Y., Nelson J.B., Jacky B.P.S., Aoki K.R.
Botulinum neurotoxin serotype A specific cell-based potency assay to replace the mouse bioassay.
PLoS ONE 7:E49516-E49516(2012)

Patent=US9249216
Fernandez-Salas E., Wang J., Garay P.E., Wong L.S., Hodges D.D., Aoki K.R.
Immuno-based botulinum toxin serotype A activity assays.
Patent number US9249216, 02-Feb-2016

Cross-references
Encyclopedic resources Wikidata; Q54584454
Entry history
Entry creation05-Mar-2018
Last entry update10-Sep-2024
Version number5