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Cellosaurus T-47D shPARG (CVCL_RA94)

[Text version]
Cell line name T-47D shPARG
Synonyms shPARG T47D
Accession CVCL_RA94
Resource Identification Initiative To cite this cell line use: T-47D shPARG (RRID:CVCL_RA94)
Comments Population: Caucasian.
Knockout cell: Method=shRNA knockdown; HGNC; HGNC:8605; PARG.
Omics: Poly-ADP-ribosylation by proteomics.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Leu194Phe (c.580C>T); ClinVar=VCV000127817; Zygosity=Homozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0553 (T-47D)
Sex of cell Female
Age at sampling 54Y
Category Cancer cell line
Publications

PubMed=29166620; DOI=10.1016/j.celrep.2017.10.106; PMCID=PMC5728415
Zhen Y.-L., Zhang Y.-J., Yu Y.-H.
A cell-line-specific atlas of PARP-mediated protein Asp/Glu-ADP-ribosylation in breast cancer.
Cell Rep. 21:2326-2337(2017)

Cross-references
Cell line databases/resources cancercelllines; CVCL_RA94
Encyclopedic resources Wikidata; Q54971342
Entry history
Entry creation05-Mar-2018
Last entry update19-Dec-2024
Version number10