Cellosaurus cell line U-CH14 (CVCL

Cellosaurus U-CH14 (CVCL_RA86)

[Text version]

Cell line name

U-CH14

Synonyms

UCH14

Accession

CVCL_RA86

Resource Identification Initiative

To cite this cell line use: U-CH14 (RRID:CVCL_RA86)

Comments

Doubling time: ~10 days (PubMed=28515451); 44 days (Chordoma Foundation).
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Bone, cranium, clivus; UBERON=UBERON_0004108.

Sequence variations

Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=28515451).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro72Arg (c.215C>G); ClinVar=VCV000012351; Zygosity=Unspecified (PubMed=28515451).

Disease

Clivus chordoma (NCIt: C5412)
Chordoma (ORDO: Orphanet_178)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

79Y

Category

Cancer cell line

STR profile

Source(s): PubMed=28515451

Markers:

Amelogenin	X,Y
CSF1PO	10,11
D3S1358	17
D7S820	8,10
D8S1179	13,14
D13S317	10,12
D16S539	11,12
D18S51	14
Penta D	14,15
Penta E	7,19
TH01	10
TPOX	8

Web pages

https://www.chordomafoundation.org/researchers/disease-models/u-ch14/

Publications

PubMed=28515451; DOI=10.1038/s41598-017-02174-5; PMCID=PMC5435709
Jager D., Barth T.F.E., Bruderlein S., Scheuerle A., Rinner B., von Witzleben A., Lechel A., Meyer P., Mayer-Steinacker R., von Baer A., Schultheiss M., Wirtz C.R., Moller P., Mellert K.
HOXA7, HOXA9, and HOXA10 are differentially expressed in clival and sacral chordomas.
Sci. Rep. 7:2032-2032(2017)

Cross-references

Cell line databases/resources

cancercelllines; CVCL_RA86

Encyclopedic resources

Wikidata; Q54973616

Gene expression databases

GEO; GSM2495964
GEO; GSM2495965
GEO; GSM2495966

Entry history

Entry creation

05-Mar-2018

Last entry update

19-Dec-2024

Version number