ID   Nalm6-Fluc-hNIS
AC   CVCL_RA35
DR   cancercelllines; CVCL_RA35
DR   Imanis; CL143
DR   Wikidata; Q54907444
CC   Population: Caucasian.
CC   Characteristics: Reporter cell line, transfected with the LV-Luc2-P2A-hNIS vector encoding for luciferase linked via a P2A cleavage peptide to the human SLC5A5 gene and under control of the spleen focus-forming virus (SFFV) promoter.
CC   Sequence variation: Gene fusion; HGNC; 50800; DUX4 + HGNC; 5477; IGH; Name(s)=IGH-DUX4; Note=The translocation occurs in the silenced IGH allele (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 3236; EGFR; Simple; p.Arg1068Ter (c.3202C>T); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Ala146Thr (c.436G>A); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 9864; RARA; Simple; p.Gln45Ter (c.133C>T); ClinVar=VCV000393019; Zygosity=Heterozygous (from parent cell line).
CC   Transfected with: HGNC; 11040; SLC5A5.
CC   Transfected with: UniProtKB; P08659; Firefly luciferase.
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
DI   NCIt; C9143; Adult B acute lymphoblastic leukemia
DI   ORDO; Orphanet_99860; Precursor B-cell acute lymphoblastic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0092 ! NALM-6
SX   Male
AG   19Y
CA   Cancer cell line
DT   Created: 05-03-18; Last updated: 30-01-24; Version: 11
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