ID   MCF-7-BAG
AC   CVCL_R954
SY   MCF-7 BAG
DR   cancercelllines; CVCL_R954
DR   Wikidata; Q54904330
RX   PubMed=1384607;
CC   Population: Caucasian.
CC   Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00722; Escherichia coli beta-galactosidase (lacZ).
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C4194; Invasive breast carcinoma of no special type
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0031 ! MCF-7
SX   Female
AG   69Y
CA   Cancer cell line
DT   Created: 05-11-13; Last updated: 10-09-24; Version: 19
//
RX   PubMed=1384607; DOI=10.1016/0959-8049(92)90245-W;
RA   Brunner N., Thompson E.W., Spang-Thomsen M., Rygaard J., Dano K.,
RA   Zwiebel J.A.;
RT   "lacZ transduced human breast cancer xenografts as an in vivo model
RT   for the study of invasion and metastasis.";
RL   Eur. J. Cancer 28A:1989-1995(1992).
//