Cellosaurus logo
expasy logo

Cellosaurus CHO/IR/IRS-1 (CVCL_R865)

[Text version]
Cell line name CHO/IR/IRS-1
Synonyms CHO-IR/IRS-1; CHO IR/IRS-1; CHO-IR/IRS1
Accession CVCL_R865
Resource Identification Initiative To cite this cell line use: CHO/IR/IRS-1 (RRID:CVCL_R865)
Comments Genetic integration: Method=Transfection/transduction; Gene=HGNC; 6091; INSR.
Genetic integration: Method=Transfection/transduction; Gene=RGD; 2922; Irs1.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_R864 (CHO/IR)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=1385403; DOI=10.1016/S0021-9258(18)41723-1
Sun X.-J., Miralpeix M., Myers M.G. Jr., Glasheen E.M., Backer J.M., Kahn C.R., White M.F.
Expression and function of IRS-1 in insulin signal transmission.
J. Biol. Chem. 267:22662-22672(1992)

PubMed=10389839; DOI=10.2337/diabetes.48.7.1359
Sun X.-J., Goldberg J.L., Qiao L.-Y., Mitchell J.J.
Insulin-induced insulin receptor substrate-1 degradation is mediated by the proteasome degradation pathway.
Diabetes 48:1359-1364(1999)

Cross-references
Encyclopedic resources Wikidata; Q54813158
Entry history
Entry creation05-Nov-2013
Last entry update10-Sep-2024
Version number12